Hereditary Breast Cancer Panel
Also known as Familial, Multi-Gene Cancer, BRCA, Li-Fraumeni syndrome, Cowden syndrome, HBOC, BRACA, BRCA1/2, CHECK2, HNPCC, Lynch Syndrome, Inherited Cancer Panel, Cancer Genes, Hereditary Cancer
What it measures
- ResultLOINC 50398-7
- GeneLOINC 48018-6
- VariantLOINC 69548-6
- ClassificationLOINC 53037-8
- Gene 2LOINC 48018-6
- Variant 2LOINC 69548-6
- Classification 2LOINC 53037-8
- Gene 3LOINC 48018-6
- Variant 3LOINC 69548-6
- Classification 3LOINC 53037-8
- Gene 4LOINC 48018-6
- Variant 4LOINC 69548-6
- Classification 4LOINC 53037-8
- Gene 5LOINC 48018-6
- Variant 5LOINC 69548-6
- Classification 5LOINC 53037-8
- Vus(S)LOINC 82939-0
- Gene ListLOINC 36908-2
- Clinical InterpretationLOINC 50398-7
- Variant InformationLOINC 82939-0
- ReviewerLOINC 69047-9
- ResourcesLOINC 8266-9
- Methods and LimitationsLOINC 77202-0
- Additional InformationLOINC 8266-9
Before the visit
Saliva: Do not eat, drink, smoke or chew gum for 30 minutes before collection. Buccal swab: Please refer to user instructions provided with kit. Ensure the sponge tip does not come into contact with any surface prior to collection. Do not eat, drink, smoke, or chew gum for 30 minutes before collection. Do not touch swab tips or allow contact with any other object.
Specimen
- Specimen
- 5 mL whole blood collected in an EDTA (lavender-top) or ACD (yellow-top) tube
- Minimum volume
- 2 mL whole blood • 2 mL saliva • 1 buccal swab • 10 mg skin fibroblasts • 2 flasks 75% confluent
- Also accepted
- 2 mL saliva to "fill to" line collected in OGD-500, Oragene-Dx Collection Kit or; 1 buccal swab submitted in OCD-100A buccal kit (ORAcollect-Dx Collection Kit) or; 10 mg skin fibroblasts collected in sterile plastic container or; 2 flasks skin fibroblasts collected in each of two separate sterile T25 culture flasks or equivalent with 80-100% confluent growth
- Container
- EDTA (lavender-top) tube or ACD (yellow-top) tube
- Temperature
- Room temperature
Do not hold specimen. Forward to laboratory when specimen arrives. Whole blood: Normal phlebotomy procedure. Specimen stability is crucial. Store and ship room temperature immediately. Do not freeze. Saliva: 2 mL saliva collected in the Oragene-Dx collection kit up to the "fill to" line (OGD-500/OGD-600, OGD-510/OGD-610). Do not remove the plastic film from the funnel lid. For fibroblasts and skin fibroblasts, call 1-866-GENEINFO (1-866-436-3463) prior to collecting and ordering.
Billing
CPT 81432